Antep previously used to be known as Antep in Ottoman Empire. It is a part of the southeastern Anatolia region. It is the sixth most populous city in Turkey and it is one of the oldest civilizations and cities inhabited in the world. There are several theories attached to the name Antep. According to a legend it was derived from Khantap meaning "king's land" in the Hittite language and in Arabic and Aramaic language that means "spring". In February 1921, the Republic of Turkey honored the city as Ghazi Antep literally meaning "Antep the war hero" thanks to its participation in the Turkish War of Independence.
Gaziantep was part of Yamhad until conquered by the Hittites. The signs of the settlement go back to the 4th millennium BC. It is also considered to be the probable site of the Hellenistic city of Antiochia in the Taurus Mountains. It has famous Gaziantep Fortress and the Ravanda citadel restored in the 6th century.
The city was conquered in 661 AD by Umayyads and the Abbasids in 750. It became a battleground of Arab-Byzantine wars. It was famously ruled by Seljuk Turk and remained its part until the Ottoman conquest. Gaziantep was captured by the Ottoman Empire in 1516 and became the center of commerce along the trade routes. It had around 3900 shops and covered bazaars and had mainly Muslim concentrated population. But it had a sizeable proportion of Armenians and Christians.